Emerging pollutant transformation and reactive oxygen species formation by oxygenase enzymes in different microbiomes
Cluster of Excellence Work Package: WP 3.2
Project description:
This subproject aims to investigate the transformation of emerging pollutants, such as tire additives, pharmaceuticals, and consumer products, by oxygenase enzymes in various microbiomes. Oxygenase enzymes play a crucial role in degrading pollutants in the environment by transforming a wide range of compounds into more polar and bioavailable products. However, under certain conditions, these enzymes exhibit poor efficiency in oxygen utilization, leading to the unintended production of reactive oxygen species (ROS).
The PhD
candidate in this project will perform exposure experiments with emerging
pollutants and microbial communities from soil, freshwater, wastewater, and the
human lung. In addition, methods will be developed to identify transformation
products and quantify ROS. The outcomes of these experiments will determine
whether a negative impact of (emerging) pollutants on environmental and human
microbiomes can arise not only from the toxicity of the pollutants and their
transformation products but also from the production of ROS by oxygenase
enzymes. The ideal candidate has a background in environmental or analytical
chemistry and a keen interest in studying organic pollutant transformation with
high-resolution mass spectrometry and/or stable isotope techniques.
Apply now https://weblogin.univie.ac.at/idp/profile/SAML2/POST/SSO?execution=e5s1
How to apply https://microplanet.at/howtoapply
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